E-Point Septal Separation (EPSS)

EPSS is a measurement used in echocardiography to assess left ventricular function. It is the distance between the E-point of the mitral valve and the interventricular septum during diastole.

• Distance between anterior leaflet of mitral valve and septum during early diastole
• Obtained in PSLA view (need LV horizontal)
• Use M mode and place cursor over tip of mitral valve
• In M mode measure distance between mitral E wave and LV septum
• Values: less than 8 is normal EF, 8-18 mild-moderate reduced EF, and over 18 mm is severely reduced EF
• Limitations: mitral valvopathies, arrhythmia

Normal Values

• Normal EPSS: < 7 mm
• Mild LV dysfunction: 7-10 mm
• Moderate LV dysfunction: 10-15 mm
• Severe LV dysfunction: > 15 mm